Quinolones, Cinoxacin, Ciprofloxacin, Grepafloxacin, Levofloxacin, Nalidixic acid, Norfloxacin, Ofloxacin. Sulphonamides, Co-trimoxazole, Sulfadiazine, Sulfadimidine.
Drug treatment for Hansen's disease (Leprosy)
Hansen's disease, more commonly known as leprosy, is a bacterial infection caused by Mycobacterium leprae. It is rare in the United Kingdom, but relatively common in parts of Africa, Asia, and Latin America.
The disease progresses slowly, first affecting the peripheral nerves and causing loss of sensation in the hands and feet. This leads to frequent unnoticed injuries and consequent scarring, Later, the nerves of the face may also be affected.
Treatment uses three drugs together to prevent the development of resistance. Usually, Dapsone, Rifampicin and Clofazimme will be given for at least 2 years. If one of these cannot be used, then a second line drug (Ofloxacin Mmocycline or Clarithromycin) might be substituted' Complications during treatment may require use of Prednisolone, Aspirin, Chloroquine, or even Thalidomide
Friday, May 25, 2007